Hypoxia inducible factor and microvessels in peri implantation endometrium of women with recurrent miscarriage

Wednesday, June 1, 2016
Expression of hypoxia inducible factor 1a and vascularization status in peri-implantation endometrium is altered in the nonconception cycles of women with a history of recurrent miscarriage.

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Expression of GRIM 19 in adenomyosis and its possible role in pathogenesis

Friday, April 1, 2016
Decreased expression of GRIM-19 may play a role in adenomyosis by regulating apoptosis and angiogenesis.

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Evaluation of the antiproliferative proapoptotic and antiangiogenic effects of a double-stranded RNA mimic complexed with polycations in an experimental mouse model of leiomyoma

Monday, February 1, 2016
Polyinosinic-polycytidylic acid complexed with polyethylenimine clearly decreased angiogenesis and promoted apoptosis in a mouse model of leiomyoma, but prolonged treatments may be necessary to affect lesion size.

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Evaluation of the potential therapeutic effects of a double stranded RNA mimic complexed with polycations in an experimental mouse model of endometriosis

Thursday, October 29, 2015
Polyethyleneimine prevented angiogenesis and promoted apoptosis in a mouse model of endometriosis, but prolonged treatments over time may be necessary to detect an effect of this compound on lesion size.

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Differential expression of vascular endothelial growth factor angiogenic factors in different endometrial compartments in women who have an elevated progesterone level before oocyte retrieval during in vitro fertilization Embryo transfer treatment

Tuesday, September 29, 2015
Altered expression of vascular endothelial growth factor angiogenic factors in peri-implantation endometrium may provide an explanation for the impairment of endometrial receptivity in women who have high P levels before oocyte retrieval.

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Expression of GRIM 19 in missed abortion and possible pathogenesis

Monday, December 29, 2014
Through a case-control study, the GRIM-19 deficiency in the villus was found may be associated with missed abortion via increasing apoptosis and affecting angiogenesis.

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In search of signaling pathways critical for ovarian graft reception Akt1 is essential for long term survival of ovarian grafts

Friday, January 31, 2014
Akt1 has a critical role in ovarian graft reception: although ovarian grafts lacking Akt1 activity survive the immediate posttransplantation period, long-term survival of the graft is impaired.

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Effect of oxygen tensions on the proliferation and angiogenesis of endometriosis heterograft in severe combined immunodeficiency mice

Friday, January 31, 2014
Oxygen tensions can influence the growth patterns of endometriosis implants in a SCID mouse model. Hypoxia pretreatment promoted the proliferation and angiogenesis of endometriosis, whereas hyperoxia pretreatment demonstrated the opposite effect.

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Delta like ligand 4 regulates vascular endothelial growth factor receptor 2 driven luteal angiogenesis through induction of a tip stalk phenotype in proliferating endothelial cells

Wednesday, November 27, 2013
Blockade of Dll4 in an in vivo rodent model shows that VEGFR2-mediated sprouting during luteal angiogenesis is modulated by the Dll4/Notch-1 pathway, which induces a tip/stalk phenotype.

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Vascular disrupting effects of combretastatin A4 phosphate on murine endometriotic lesions

Thursday, October 31, 2013
This study demonstrates for the first time a selective vascular disrupting effect of CA4P on endometriotic lesions, indicating that vascular disrupting agents may be suitable for the therapy of endometriosis.

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Transforming growth factor β1 and its receptor soluble endoglin are altered in polycystic ovary syndrome during controlled ovarian stimulation

Wednesday, July 31, 2013
Increased transforming growth factor-b1 and decreased levels of its receptor, soluble endoglin are found in women with polycystic ovarian syndrome (PCOS) and may be implicated in PCOS pathogenesis and its increased risk for ovarian hyperstimulation.

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Immature myeloid cells derived from mouse placentas and malignant tumors demonstrate similar proangiogenic transcriptional signatures

Friday, March 1, 2013
Immature myeloid cells derived from placentas and tumors show similar molecular signatures. This common gene expression pattern may indicate that these cells share the same origins and functions.

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Decreased endometrial vascularity in patients with antiphospholipid antibodies associated recurrent miscarriage during midluteal phase

Thursday, November 29, 2012
We found a decrease in endometrial-subendometrial vascularity as shown by three-dimensional ultrasonography and power Doppler angiography in antiphospholipid antibodies–associated recurrent miscarriage patients during the peri-implantation period.

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Effect of antiangiogenic treatment on peritoneal endometriosis associated nerve fibers

Thursday, November 1, 2012
Because nerve fibers present in endometriosis play an important role in pain mechanisms, antiangiogenic treatment that decreases nerve fibers provides a novel therapeutic approach.

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