Friday, August 30, 2013Polar body biopsy combined with array comparative genomic hybridization allows detection of maternal chromosomal aberrations. Although it has limitations, it can be seen as an alternative to blastomere and trophectoderm biopsy.
Friday, June 28, 2013The Blastocyst Euploid Selective Transfer (BEST) Trial demonstrated that single euploid blastocyst transfer results in ongoing pregnancy rates that are equivalent to transferring two untested blastocysts, while dramatically reducing the risk of multiple gestations.
Preimplantation genetic screening using fluorescence in situ hybridization in patients with repetitive implantation failure and advanced maternal age Two randomized trials
Thursday, March 28, 2013Preimplantation genetic screening using fluorescence in situ hybridization improves live-birth rates in patients with repetitive implantation failure or advanced maternal age.
Thursday, March 28, 2013Reflections on "Preimplantation genetic screening using fluorescence in situ hybridization in patients with repetitive implantation failure and advanced maternal age: two randomized trials" by Rubio et al.
Monday, March 18, 2013The use of array comparative genomic hybridization in preimplantation genetic screening produces high pregnancy rates with embryo biopsy at different stages.
Wednesday, January 2, 2013We describe the role of mitochondrial dysfunction in ovarian senescence and suggest a treatment to improve reproductive outcome with mitochondrial nutrients.
Wednesday, January 2, 2013Telomere dynamics differ between the female and male germ lines: oocytes have short telomeres, and their erosion recapitulates the reproductive aging phenotype, and telomere length in sperm increases with age.
Thursday, September 27, 2012In this study analyzing embryo morphology and chromosomal status in relation to rate of embryonic developmental progression, the ability to blastulate, rather than day of blastulation, was found to significantly affect aneuploidy.
Friday, July 6, 2012
Ana Cobo, Ph.D.
Volume 98, Issue 3, Pages 600-601, September 2012
Reflections on “Oocyte vitrification does not increase the risk of embryonic aneuploidy or diminish the implantation potential of blastocysts created after intracytoplasmic sperm injection: a novel, paired randomized controlled trial using DNA fingerprinting”…