Fertility preservation utilizing controlled ovarian hyperstimulation and oocyte cryopreservation in a premenarcheal female with myelodysplastic syndrome

Capsule:
Reflections on “Fertility preservation utilizing controlled ovarian hyper-stimulation and oocyte cryopreservation in a premenarcheal female with myelodysplastic syndrome” by Reichman et al.

Authors:
Dominic Stoop, M.D., Ph.D., Michel De Vos, M.D., Ph.D., Herman Tournaye, M.D., Ph.D., Paul Devroey, M.D., Ph.D.

Volume 98, Issue 5, Pages 1121-1122, November 2012

Abstract:

Reflections on “Fertility preservation utilizing controlled ovarian hyper-stimulation and oocyte cryopreservation in a premenarcheal female with myelodysplastic syndrome” by Reichman et al.

  • Micah Hill

    Thank you for the very insightful reflections. I think the reference to the Anderson paper, which questions the potential quality of oocytes obtain from pre-pubescent girls, is very important. As the authors suggest, more series and studies will be very important to demonstrate the reproductive potential of the oocytes obtained from these patients.

  • Javier Domingo del Pozo

    Thank you for your comments. I agree with you that we must be very careful on what we recommend to preserve the fertility. One of the limitations oocyte vitrification has is the limited number of oocytes we will dispose, and so a limited number of IVF attempts. Then we have to be sure of what we are recommending to the patients, at least any procedure with proved results. I don’t know any series/results using vitrified oocytes from prepubertal girls, and so, although it might be promising, it should be recommended as experimental and I suggest only in girls with time enough to cryopreserve ovarian tissue after COH.

Translate »