Infertility trial outcomes Healthy moms and babies

Capsule:
Infertility trials should routinely report important maternal, fetal, and neonatal outcomes. These include details regarding pregnancy losses, preterm birth, pre-eclampsia, diabetes, growth restriction, genetic problems, and birth defects.

Author:
Robert Silver, M.D.

Volume 101, Issue 5, Pages 1209–1216

Abstract:
Traditionally, the primary outcome of infertility trials has been a positive pregnancy test or a clinically recognized pregnancy. However, parents desire a healthy baby that grows up to be a healthy adult, rather than a positive pregnancy test. Too often results of infertility trials are lacking in crucial obstetric details. This is problematic because treatments for infertility have the capacity to increase the risk for a variety of adverse obstetric outcomes. This review will outline important obstetric variables that should be included when reporting infertility research. The rationale for including these data, precise definitions of the variables, and cost-effective strategies for obtaining these obstetric details will be highlighted.

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