What serial hCG can tell you and cannot tell you about an early pregnancy

The measurement of serial serum hCG concentrations is an integral part of making the correct diagnosis in early pregnancy.

Beata Eva Seeber, M.D., M.S.C.E.

Volume 98, Issue 5, Pages 1074-1077, November 2012

The serial measurement of serum hCG concentrations is an important clinical tool used to differentiate normal from abnormal pregnancies. At hCG values below which ultrasonography can be diagnostic, the comparison of a patient’s hCG dynamics to those of established expected curves of rise or fall can aid the clinician in determining when to follow expectantly and when to intervene. Still, this method has some limitations and should never supersede clinical judgment based on symptoms or signs.

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