Importance of embryo transfer technique in maximizing assisted reproductive outcomes

Meticulous ET technique, aided by ultrasound guidance, is essential to optimal outcomes with assisted reproductive technology.

William B. Schoolcraft, M.D.

Volume 105, Issue 4, Pages 855-860


Embryo transfer is arguably the most critical process in the sequential events that encompass an IVF cycle. Several variables play a role in the success of a transfer, including catheter type, atraumatic technique, and the use of ultrasound guidance. The inclusion of hyaluronan in the ET media also has a benefit for implantation. Because of the adverse effects of controlled ovarian hyperstimulation on the endometrium, frozen embryo transfers have demonstrated improved pregnancy rates as well as better obstetric outcomes. This review will talk about various aspects of ET as it is currently performed, variables affecting its success, and methods of optimization.

  • This comprehensive review highlights the importance of the embryo transfer (ET) technique in ART. As the author points out “If an embryo cannot be delivered to the uterine cavity atraumatically and in a location for optimal implantation, the steps of ovarian hyperstimulation, oocyte retrieval,embryo culture, and embryo selection will have no benefit.” Given that the ET is such an integral part of what we do, it would appear that thorough training of REI fellows in the procedure is essential. Efforts to improve this are underway, and this article is a great resource to offer practical advice for those learning to perform the procedure.

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