Mosaicism Survival of the fittest versus no embryo left behind

Posted by Steven Palter, MD on Sunday, May 1, 2016 · 2 Comments

Authors:
Santiago Munné, Ph.D., James Grifo, M.D., Ph.D., Dagan Wells, Ph.D.

Volume 105, Issue 5, Pages 1146-1149

Abstract:

Reflections on “Outcomes of in vitro fertilization with preimplantation genetic diagnosis: an analysis of the United States Assisted Reproductive Technology Surveillance Data, 2011–2012” by Chang et al.

Category: Articles of Special Interest, Uncategorized · Tags: monosomy, mosaicism, PGD, PGS, trisomy

Dan Jones

Your article mentions that PGS results should be split into three categories. However you refer to the incidence of segmental losses/duplications and mosaicism in the same sentence, but then only refer to mosaicism. How should these blastocysts with structure losses or duplications be treated. The same as mosaics or something else? Thanks.
李孟儒

Do you have any ideas why euploid/aneuploid mosaics decreases with age, from 26.6% in women 42 year olds ?

Mosaicism Survival of the fittest versus no embryo left behind

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