Acute portal vein thrombosis complicating in vitro fertilization

Capsule:
After oocyte retrieval for IVF-ET, upper abdominal pain was the presenting symptom of acute portal venous thrombosis with extension into the surrounding vasculature, and was managed with anticoagulation.

Authors:
Natu Mmbaga, M.D., Saioa Torrealday, M.D., Shirley McCarthy, M.D., Ph.D., Beth W. Rackow, M.D.

Volume 98, Issue 6, Pages 1470-1473, December 2012

Abstract:

Objective:
To describe a case of acute portal vein thrombosis after IVF treatment.

Design:
Case report.

Setting:
University teaching hospital.

Patient(s):
A 39-year-old woman experienced worsening, right upper quadrant pain several days after oocyte retrieval; embryo transfer was withheld. Imaging studies revealed acute portal vein thrombosis with extension into the splenic and superior mesenteric veins.

Intervention(s):
Therapeutic anticoagulation; no embryo transfer was performed.

Main Outcome Measure(s):
Improvement in symptoms, accurate diagnosis of condition.

Result(s):
Decreased size of portal vein thrombosis and partial vessel recanalization.

Conclusion:
Thromboembolic events are a rare complication of assisted reproductive technology (ART). In women who present with upper abdominal pain during ART, portal vein thrombosis should be considered in the differential diagnosis.

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