Low birth weight Is it related to assisted reproductive technology or underlying infertility

Capsule:
We review the potential association between different components of ART and infertility with LBW, while acknowledging the limitations to interpretation of the existing literature.

Authors:
Laxmi A. Kondapalli, M.D., M.S.C.E., Alfredo Perales-Puchalt, M.D.

Volume 99, Issue 2, Pages 303-310, February 2013

Abstract:

Since 1978, we have witnessed a successful evolution of assisted reproductive technology (ART), with improvement of the pregnancy rates and a growing demand. However, in recent years, there has been increasing concern regarding its safety due to the potential health impact on its infants. The raise of the developmental origins of adult disease 25 has positioned low birth weight (LBW) as a significant health issue. Despite multiple studies have associated ART with LBW, the etiology of this association remains largely unknown. This paper reviews the potential association between different components of ART and infertility with LBW, while acknowledging the limitations to interpretation of the existing literature.

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