Embryology in the era of proteomics

Capsule:
A review of the contribution of proteomic technologies in the identification of the human embryonic secretome.

Authors:
Mandy G. Katz-Jaffe, Ph.D., Susanna McReynolds, Ph.D.

Volume 99, Issue 4, Pages 1073-1077, 15 March 2013

Abstract:

Proteomic technologies have begun providing evidence that viable embryos possess unique protein profiles. Some of these potential protein biomarkers have been identified as extracellular and could be utilized in the development of a non-invasive quantitative method for embryo assessment. The field of assisted reproductive technologies (ART) would benefit from defining the human embryonic proteome and secretome thereby expanding our current knowledge of embryonic cellular processes.

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