Fertility Pregnancy and Medical Management of Turner Syndrome in the Reproductive Years

Capsule:
Women with Turner syndrome are at high risk of maternal and fetal morbidity and mortality. Fertility preservation may be an option for some girls. They also require lifelong comprehensive screening.

Author:
Megan Freebury Karnis, M.D.

Volume 98, Issue 4, Pages 787-791, October 2012

Abstract:
Turner syndrome results in infertility in the majority of cases. Fertility preservation through the cryopreservation of oocytes or ovarian tissue may be an option for some girls with Turner syndrome. Oocyte donation results in high pregnancy rates. Those who plan to pursue pregnancy need comprehensive screening and counseling before and after conception. Pregnancies conceived with either autologous or donated oocytes are at high risk of maternal death from aortic dissection/rupture and are at high risk of serious hypertensive disorders. Reproductive aged women with Turner syndrome require ongoing screening for associated medical conditions unrelated to reproduction.

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