The use of aromatase inhibitors in in vitro fertilization

Capsule:
The use of aromatase inhibitors in IVF patients is promising. Poor responders and patients at risk of ovarian hyperstimulation syndrome or high estrogen levels may benefit.

Authors:
Juan A. Garcia-Velasco, M.D.

Volume 98, Issue 6, Pages 1356-1358, December 2012

Abstract:
The use of AIs in IVF patients is still controversial. Although the biological plausibility of the capacity of AIs in IVF patients with a poor response to COH to modulate androgens and improve cycle outcome is promising, still results should be interpreted with caution, as they need to prove their efficacy in randomized trials. They are an effective drug to drastically reduce circulating estrogen levels in those patients at risk of OHSS, thrombosis or hormonal-dependent diseases.

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