Dyspareunia and Sexual Dysfunction in Women Seeking Fertility Treatment

In a case-control study comparing 75 infertile women and 210 controls, no significant differences were found in the rates of dyspareunia or sexual dysfunction.

Abby P. Furukawa, M.D., Phillip E. Patton, M.D., Paula Amato, M.D., Hong Li, M.P.H., M.S., Catherine M. Leclair, M.D.

Volume 98, Issue 6, Pages 1544-1548.e2, December 2012


To compare rates of dyspareunia in infertile women and healthy controls. Secondary aims are to determine whether demographic characteristics, rates of sexual dysfunction, and baseline depression status differ between the two groups.

A case-control study.

University-based faculty fertility and OB/GYN generalist clinics.

Seventy-five infertile female subjects presenting to infertility clinic and two hundred ten (210) women presenting to the generalist clinic for their annual exam

Completion of an anonymous survey including demographic information, the Female Sexual Function Index (FSFI), Patient-Health Questionnaire-9 (PHQ-9), and original questions regarding sexual pain.

Main Outcome Measures:
Rate of dyspareunia and sexual dysfunction.

There were no significant differences in rates of dyspareunia (37.6% controls vs. 30.7% study, p = 0.28) or the rate of sexual dysfunction (31.9% controls versus 37.3% study, p = 0.39). Infertile women had more frequent intercourse than controls and were more likely to be married. There were otherwise no differences in baseline rates of depression, demographic characteristics, or individual domains scores of the FSFI.

Women seeking fertility treatment had similar rates of dyspareunia and sexual dysfunction compared to controls.

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