Healthcare utilization and costs in women diagnosed with endometriosis before and after diagnosis A longitudinal analysis of claims databases

Capsule:
Endometriosis is associated with a substantial economic burden during the 5-year periods both before and after diagnosis; healthcare utilization and costs peak during the first year after diagnosis among endometriosis patients.

Authors:
Mahesh Fuldeore, Ph.D., Hongbo Yang, Ph.D., Ella Xiaoyan Du, M.E.Sc., Ahmed M. Soliman, Ph.D., Eric Q. Wu, Ph.D., Craig Winkel, M.D.

Volume 103, Issue 1, Pages 163-171

Abstract:

Objective:
To assess healthcare resource utilization and costs during the 5 years before and 5 years after diagnosis among women with endometriosis, in comparison with women without endometriosis.

Design:
Longitudinal, retrospective, case–control study.

Setting:
None.

Patient(s):
A total of 37,570 matched pairs of women with and without (controls) endometriosis were identified from the Truven Health MarketScan claims database (2000–2010).

Intervention(s):
None.

Main Outcome Measure(s):
Annual healthcare resource utilization and costs (in 2010 US dollars) were evaluated for the 5 years before and 5 years after diagnosis.

Result(s):
Mean patient age at index (first diagnosis) date was 36.4 years for endometriosis patients and controls. Endometriosis patients had a higher utilization of outpatient and emergency room services during each pre- and postindex year, and a higher utilization of inpatient services during the last preindex year and all 5 postindex years. Total costs were highest in the first postindex year for endometriosis patients, reaching $13,199, compared with $3,747 for controls. Annual costs were significantly higher for patients than controls during each pre- and postindex year; overall, the cost difference was $26,305 over 10 years: $7,028 in the 5 years before diagnosis and $19,277 in the 5 years after diagnosis.

Conclusion(s):
Endometriosis poses a significantly high economic burden, both before and after diagnosis. The highest resource utilization and costs experienced by endometriosis patients occur in the first year after diagnosis.

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