Healthy live birth using theophylline in a case of retrograde ejaculation and absolute asthenozoospermia
Theophylline was an efficient tool in stimulating immotile spermatozoa in patients with retrograde ejaculation.
Ebner Thomas, Ph.D., Shebl Omar, M.D., Mayer Richard Bernhard, M.D., Moser Marianne, Ph.D., Costamoling Walter, M.D., Oppelt Peter, M.D.
Volume 101, Issue 2, Pages 340-343, February 2014
To analyze whether the use of ready-to-use theophylline is a feasible option in a case of retrograde ejaculation and absolute asthenozoospermia.
In vitro fertilization unit of a public hospital.
Thirty-one-year-old nulliparous woman, and 39-year-old male with retrograde ejaculation and absolute asthenozoospermia.
Retrieval of postejaculatory urine, restoration of motility using a methylxanthine, intracytoplasmic sperm injection, single-embryo transfer.
Main Outcome Measure(s):
Sperm motility, fertilization, embryo quality, live birth.
Successful fertilization and a single-embryo transfer resulted in a healthy live birth.
Theophylline turned out to be a safe, efficient agent for stimulating immotile spermatozoa in patients with retrograde ejaculation.