Thin endometrium in donor oocyte recipients Enigma or obstacle for implantation

Capsule:
Thin endometrium does not seem to influence oocyte donation outcome.

Authors:
Lena Dain, M.D., David Bider, M.D., Jacob Levron, M.D., Viktor Zinchenko, M.D., Sharon Westler, Martha Dirnfeld, M.D.

Volume 100, Issue 5, Pages 1289-1295.e2, November 2013

Abstract:

Objective:
To evaluate the combined effect of endometrial thickness and anatomic uterine factors on clinical outcome in oocyte donation recipients.

Design:
Retrospective analysis of oocyte donation cycles conducted between 2005 and 2010.

Setting:
Two private IVF centers.

Patient(s):
A total of 737 donor oocyte cycles.

Intervention(s):
None.

Main Outcome Measure(s):
Clinical pregnancy and live birth rates.

Result(s):
No statistically significant difference was found in clinical pregnancy rates and live birth rates in cycles with endometrial thickness <6 mm compared with those with endometrial thickness >10 mm. However, a relatively high rate of live births was found within a medium range of endometrial thickness (8.2–10 mm). All intrauterine adhesion cases occurred in cycles with thinner endometrium.

Conclusion(s):
No statistically significant difference was found in clinical pregnancy rates and live birth rates in cycles with endometrial thickness <6 mm compared with those with thickness >6 mm. A relatively high rate of live births was found within a medium range of endometrial thickness (9.1–10 mm).

Translate »