Childhood implications of parental aging
We discuss how societal changes have led to increasing parental age with potential impact on childhood health. The differences in gamete biology may be keys to understanding these risks.
Marcelle I. Cedars, M.D.
Volume 103, Issue 6, Pages 1379-1380
Men and women are increasingly delaying childbearing to the late 30s, the 40s and beyond. The implications of this societal change on childhood health and well-being have only recently been a focus of research. There are known increased perinatal risks associated with increasing maternal age, while paternal age seems to have a potentially greater negative impact on childhood health. Understanding the mechanisms underlying the aging of sperm and eggs, and how these changes impact offspring, is a critical next step as we work to help patients build healthy families.