Women infected with human immunodeficiency virus type 1 have poorer assisted reproduction outcomes A case control study

Sunday, May 1, 2016
Human immunodeficiency virus 1 infection in women is associated with poorer assisted reproductive technology (ART) outcomes in a match-paired, case-control study, which indicates no ART delay in cases with HIV-1 controlled infection.

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Improving reporting of research reports

Sunday, May 1, 2016

Authors:
Robert A. Wild, M.D., M.P.H., Ph.D.…

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Introduction Access to fertility care

Sunday, May 1, 2016
Despite impressive advances in the field of reproductive medicine, access to care is a persisting challenge. These articles explore barriers to fertility care and propose a constructive path forward.

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Practice patterns satisfaction and demographics of reproductive endocrinologists Results of the 2104 Society for Reproductive Endocrinology and Infertility Workforce Survey

Sunday, May 1, 2016
Members of the Society of Reproductive Endocrinologists and Infertility have a focused practice, sense a change in scope of practice, envision minimal growth, and have very high professional satisfaction.

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Position on reproductive donors and smallpox vaccine A committee opinion

Sunday, May 1, 2016

Capsule:
The suitability of reproductive donors who have received smallpox vaccine is discussed.…

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Prospective evaluation of the impact of intermenstrual bleeding on natural fertility

Sunday, May 1, 2016
An episode of intermenstrual bleeding statistically significantly decreases the odds of conception in the current cycle but does not appear to negatively impact a woman’s future reproductive potential.

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The relationship between recurrent pregnancy loss and the male contribution

Sunday, May 1, 2016

Author:
Eve C. Feinberg, M.D.…

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Estrogen receptor β regulates endometriotic cell survival through serum and glucocorticoid regulated kinase activation

Sunday, May 1, 2016
Estrogen receptor (ER) b is aberrantly overexpressed in ectopic endometriotic tissues. This study demonstrates that ERb regulates the transcription of SGK1, a kinase that promotes apoptotic resistance in endometriosis via FOXO3 inactivation.

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Tissue extraction technique at the time of laparoscopic myomectomy

Sunday, May 1, 2016

Authors:
Tommaso Falcone, M.D., Rebecca Flyckt, M.D.…

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Spontaneous endogenous pulsatile release of kisspeptin is temporally coupled with luteinizing hormone in healthy women

Sunday, May 1, 2016
Measuring the plasma concentrations of kisspeptin, this study reveals groundbreaking evidence suggesting that kisspeptin and luteinizing hormone are cosecreted and temporally coupled in healthy women.

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Sequential versus Monophasic Media Impact Trial SuMMIT A paired randomized controlled trial comparing a sequential media system to a monophasic medium

Sunday, May 1, 2016
This study demonstrates that the usable blastocyst rate is greatest after culture in sequential media in comparison with monophasic; however, no difference exists in timing of blastulation, aneuploidy, or sustained implantation rate.

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Sonographic markers of ovarian morphology but not hirsutism indices predict serum total testosterone in women with regular menstrual cycles

Sunday, May 1, 2016
We discuss how total testosterone levels were predicted by sonographic markers of ovarian morphology, not hirsutism scores; and how the predictive value of ovarian morphology for total testosterone differed by menstrual cycle status.

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Recommendations for development of an emergency plan for in vitro fertilization programs A committee opinion

Sunday, May 1, 2016
All in vitro fertilization programs and clinics should have plans for the protection of fresh and cryopreserved human tissue and continuation of patient care in the event of an emergency or natural disaster.

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Effects of maternal age on euploidy in a large cohort of embryos analyzed with 24 chromosome single nucleotide polymorphism based preimplantation genetic screening

Sunday, May 1, 2016
For 37,711 embryos analyzed with 24-chromosome single-nucleotide polymorphism–based preimplantation genetic screening, the number, proportion, and probability of embryos testing as euploid per IVF cycle were stratified by maternal age.

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Diminished ovarian reserve Is it a neglected cause in the assessment of recurrent miscarriage A cohort study

Sunday, May 1, 2016
Diminished ovarian reserve may be a hidden cause for recurrent miscarriage regardless of maternal age.

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Cited2 protein level in cumulus cells is a biomarker for human embryo quality and pregnancy outcome in one in vitro fertilization cycle

Sunday, May 1, 2016
Higher Cited2 level in human cumulus cells is associated with decreasing embryo quality and pregnancy outcome in IVF patients, which may be attributed to apoptosis and abnormal gluconeogenesis in cumulus cells.

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Low dose human chorionic gonadotropin alone can complete follicle maturity Successful application to modified natural cycle in vitro fertilization

Sunday, May 1, 2016
Low-dose human chorionic gonadotropin can be used to complete follicle maturity after gonadotropin releasing hormone antagonist administration in the late follicular phase of a natural cycle, leading to successful pregnancies in modified natural cycle in vitro fertilization.

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Can we modify assisted reproductive technology practice to broaden reproductive care access

Sunday, May 1, 2016
Access to care may be enhanced by modifying standard assisted reproductive technology practice to make fertility treatment cheaper, simpler, and better tolerated by patients.

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Searching for a common mechanism for placenta-mediated pregnancy complications and cardiovascular disease Role of lipoprotein a

Sunday, May 1, 2016
This study shows an association between lipoprotein(a) concentrations and history of stillbirth and preeclampsia. This well known atherothrombotic marker might represent one of the mechanisms shared by obstetrical and cardiovascular disease.

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Potential role of circulating microRNAs as a biomarker for unexplained recurrent spontaneous abortion

Sunday, May 1, 2016
Four circulating miRNAs (miR-320b, miR-146b-5p, miR-221-3p, miR-559) were up-regulated and one miRNA (miR-101-3p) was down-regulaed in unexplained recurrent spontaneous abortion (URSA). These circulating microRNAs may be involved in URSA pathogenesis and provide a promising new diagnostic biomarker for URSA.

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Working memory in women with polycystic ovary syndrome

Sunday, May 1, 2016

Author:
Courtney A. Marsh, M.D., M.P.H.…

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Position statement on West Nile virus A committee opinion

Sunday, May 1, 2016
It is recommended that practitioners defer gamete donors who have confirmed or suspected West Nile virus infections.

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Who receives a medical evaluation for infertility in the United States

Sunday, May 1, 2016
In addition to financial access influencing who receives a medical evaluation for infertility, demographic and healthy lifestyle characteristics are associated with a medical evaluation for infertility among infertile women.

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Association of the very early rise of human chorionic gonadotropin with adverse outcomes in singleton pregnancies after in vitro fertilization

Sunday, May 1, 2016
Slower very early first-trimester human chorionic gonadotropin rise is associated with low birth weight but not gestational age at delivery among singleton in vitro fertilization conceptions.

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Sequencing of FTO and ALKBH5 in men undergoing infertility work-up identifies infertility associated variant and two missense mutations

Sunday, May 1, 2016
Sequencing of the ALKBH5 and FTO genes in patients with male factor infertility identified one genetic variant in the FTO gene to be associated with reduced semen quality and two FTO missense variants.

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Number of biopsied trophectoderm cells is likely to affect the implantation potential of blastocysts with poor trophectoderm quality

Sunday, May 1, 2016
We found that the implantation potential is negatively affected by the biopsied cell number in blastocysts with poor trophectoderm morphological score.

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Does polycystic ovarian syndrome affect cognition A functional magnetic resonance imaging study exploring working memory

Sunday, May 1, 2016
Antiandrogenic treatment appears to have a beneficial effect on working memory in women with polycystic ovary syndrome.

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Discriminant analysis forecasting model of first trimester pregnancy outcomes developed by following 9963 infertile patients after in vitro fertilization

Sunday, May 1, 2016
A forecasting method was developed to predict first trimester pregnancy outcomes through ultrasound scan on days 27–29 after ET and the follow-up can be planned accordingly.

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To delay or not to delay a frozen embryo transfer after a failed fresh embryo transfer attempt

Sunday, May 1, 2016
Frozen embryo transfers performed immediately after fresh in vitro fertilization cycles had clinical pregnancy rates similar to those postponed to a later time. Therefore, deferring frozen embryo transfers may unnecessarily prolong the time to pregnancy.

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Live birth of twins derived from zona free oocytes

Sunday, May 1, 2016
A 34-year-old woman conceived through in vitro fertilization using autologous zona-free oocytes after intracytoplasmic sperm injection and embryo transfer of morula and blastocyst, resulting in a term twin live birth.

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