Magnetic nanoparticles as a new approach to improve the efficacy of gene therapy against differentiated human uterine fibroid cells and tumor initiating stem cells
Wednesday, June 1, 2016We discuss whether efficient transduction and subsequent elimination of fibroid tumor-initiating stem cells during debulking of tumor cells will aid in completely eradicating the tumor as well as decreasing the likelihood of recurrence.
Wednesday, June 1, 2016The study found that cancerous tissues of female reproductive tissues, uterine polyps, and those collected from women with a history of smoking are characterized by altered metals status.
Evaluation of intrauterine insemination practices A 1 year prospective study in seven French assisted reproduction technology centers
Wednesday, June 1, 2016Gonadotropin-releasing hormone antagonist used with multifollicular stimulation allows high delivery rates in intrauterine insemination.
Depression anxiety and antidepressant treatment in women Association with in vitro fertilization outcome
Wednesday, June 1, 2016A diagnosis of depression, anxiety, or treatment with antidepressants before an in vitro fertilization cycle had a slight negative association with pregnancy and live birth but not miscarriage.
Wednesday, June 1, 2016FMR1 CGG repeat lengths within the normal range were not independently associated with ovarian stimulation response or assisted reproduction outcomes.
Wednesday, June 1, 2016The available literature on the treatment of unexplained infertility reflects the heterogeneity of clinical practice. Adequately powered, randomized trials are needed to directly compare the efficacy of these treatments.
Wednesday, June 1, 2016Women experience a significant reduction in fecundity and an increase in the probability of infertility in the late thirties. At any age >30 years, women, who have never conceived before, have a lower probability of conception.
Proposal for a national registry to monitor women with Turner syndrome seeking assisted reproductive technology
Wednesday, June 1, 2016
Angela E. Lin, M.D., Megan F.…
In vitro fertilization outcomes after fresh and frozen blastocyst transfer in South Asian compared with white women
Wednesday, June 1, 2016In vitro fertilization outcomes among South Asian women are similar to Caucasian women in frozen embryo transfer cycles and significantly lower in fresh in vitro fertilization cycles.
Wednesday, June 1, 2016The histology, ultrastructure, and viability of follicles and stromal cells are better preserved after vitrification of human ovarian cortical strips with slush nitrogen compared with liquid nitrogen.
Gonadotropin releasing hormone and gonadotropin releasing hormone receptor are expressed at tubal ectopic pregnancy implantation sites
Wednesday, June 1, 2016This study discusses the expression of gonadotropin-releasing hormone (GnRH) and its receptor at tubal ectopic pregnancy implantation sites, and investigates the role of GnRH and a GnRH antagonist in regulating trophoblastic BeWo cell viability.
Wednesday, June 1, 2016Reflections on "Predictors of pregnancy and live-birth in couples with unexplained infertility following ovarian stimulation-intrauterine insemination" by Hansen et al.
Wednesday, June 1, 2016The magnetic resonance structured report in infertility defines and proposes a standardized magnetic resonance imaging structured report in patients with infertility to have clinical completeness regarding possible diagnosis and severity.
Wednesday, June 1, 2016Higher pretreatment whole grain intake was related to a higher probability of live birth among women undergoing in vitro fertilization.
Wednesday, June 1, 2016
Rene Frydman, M.D.
Volume 105, Issue 6, Page 1445
Why is surrogacy so highly debated as a pertinent solution for women with infertility caused by uterine factors?…
Wednesday, June 1, 2016Reflections on "The impact of female age and nulligravidity on fecundity in an older reproductive age cohort" by Steiner et al.
Wednesday, June 1, 2016Adhesion fibroblasts manifested an altered metabolic profile as compared with normal peritoneal fibroblasts, which favors the glycolytic pathway, and is further altered by hypoxia.
Wednesday, June 1, 2016Inequities exist within state insurance laws that mandate coverage for infertility care. Only 8 of 15 state laws include coverage for male partners, placing undue burden on the female partner.
Wednesday, June 1, 2016Ultrasound offers descriptive and physiologic assessment of the endometrium. Current prediction of pregnancy by endometrial ultrasound is not satisfactory. Future integration of multiple variables may lead to better prediction.
Complete evaluation of anatomy and morphology of the infertile patient in a single visit The modern infertility pelvic ultrasound examination
Wednesday, June 1, 2016The concept of “one-stop shopping” for evaluating female infertility is a comprehensive ultrasound evaluating the uterus and ovaries, including the shape of the cavity, serosal surface, and tubal patency.
Predictive value of sperm morphology and progressively motile sperm count for pregnancy outcomes in intrauterine insemination
Wednesday, June 1, 2016In addition to female factors, a low percentage of morphologically normal spermatozoa and moderate number of inseminated motile spermatozoa have a positive predictive value for successful intrauterine insemination, albeit low.
Wednesday, June 1, 2016This study of the hypothalamus-hypophysis-gonad axis in children and adolescents with nonmosaic triple X syndrome found that Triple X patients showed premature activation of the gonadotropin-releasing hormone pulse generator and reduced gonadal function.
Wednesday, June 1, 2016Noninvasive imaging techniques play an important role in the female infertility diagnostic algorithm. Computerized tomographic and magnetic resonance virtual hysterosalpingography techniques allow a comprehensive assessment of the female reproductive system.
Clinical hormonal ovarian and genetic aspects of 46 XX patients with congenital adrenal hyperplasia due to CYP17A1 defects
Wednesday, June 1, 2016P450c17 deficiency due to inactivating CYP17A1 mutation in 46,XX patients is associated with primary or secondary amenorrhea, absent/sparse pubic hair, hypertension, and high prevalence of ovarian macrocysts with a risk of torsion. In patients with hypergonadotropic hypogonadism, high basal progesterone level is a hallmark for this diagnosis.
Wednesday, June 1, 2016
Robert W. Rebar, M.D.…
Validation of a next generation sequencing based protocol for 24 chromosome aneuploidy screening of blastocysts
Wednesday, June 1, 2016Our study validated multiple annealing and looping-based amplification cycle next-generation sequencing for 24-chromosome aneuploidy screening of blastocysts.
Interaction of apolipoprotein E gene polymorphisms on miscarriage risk in black and white American women
Wednesday, June 1, 2016We investigated a biracial cohort of women at the end of their reproductive life. Carrying the apolipoprotein E*2 allele was a risk factor for pregnancy loss only in white women.
Every last baby out of every last egg The appropriate goal for fertility treatment in women older than 40 years
Wednesday, June 1, 2016
Richard J. Paulson, M.D.…