Effect of ovarian stimulation and oocyte retrieval on reproductive outcome in oocyte donors

Capsule:
A cross-sectional survey of 194 previous oocyte donors performed by a standardized telephone questionnaire shows that oocyte donation does not affect donors’ short-term reproductive health.

Authors:
Dominic Stoop, M.D., Lynn Vercammen, M.D., Nikolaos P. Polyzos, M.D., Ph.D., Michel de Vos, M.D., Ph.D., Julie Nekkebroeck, Ph.D., Paul Devroey, M.D., Ph.D.
Volume 97, Issue 6 , Pages 1328-1330, June 2012

Objective:
To assess whether there is an increased risk of infertility in women that have previously undergone ovarian stimulation and oocyte retrieval for oocyte donation.

Design:
Cross-sectional survey.

Setting:
Tertiary referral center.

Patient(s):
A total of 194 past oocyte donors.

Intervention(s):
Telephone questionnaire.

Main Outcome Measure(s):
Incidence of infertility after oocyte donation.

Result(s):
Of the women who indicated having pursued conception after oocyte donation, 95% (57/60) became pregnant unassisted. Before oocyte donation, 41 women in this cohort had already been trying to conceive, of which 38 had delivered a child and 3 (7.3%) had needed infertility treatment.

Conclusion(s):
The data suggest that oocyte donation does not affect short-term reproductive health.

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