Antimullerian hormone (AMH) levels correlate independently with polycystic ovaries and ovarian hyperandrogenism. AMH levels in PCOS overlap those in volunteers with normal-variant polycystic ovaries. Only substantial AMH elevations are diagnostic of PCOS.
Male cystinosis patients are infertile. Male Ctns-/- mice (cystinosis mouse model) showed normal fertility compared with wild-type mice (measured by litter size). Also, histology of testes and epididymis as well as sperm analysis were similar in both groups.
Genetic analysis of the products of conception may provide substantial net economic benefits in evaluation of recurrent pregnancy loss.
Patients with a BMI over 30 have up to 68% lower odds of having a live birth following their first ART cycle.
The author reflects on the findings of Zhao et al. in their article “Effect of 5-aza-2′-deoxycytidine on methylation of the putative imprinted control region of H19 during the in vitro development of vitrified bovine two-cell embryos” and discusses the need for additional research and experience in epigenetics before the new technology can be applied to human IVF and ART.
A discussion is presented about the suitability of donors who have received the smallpox vaccine.
We discuss how current therapies for dysfunctional reproductive tissues are often not adequate, and the study of the tissue engineering strategies designed to repair or replace damaged organs.
Adult stem cells have been identified in human endometrium. Their ability to reconstruct endometrial tissue when transplanted into immunocompromised animals suggests their potential use for treating disorders associated with inadequate endometrium.
We present an overview of gametogenesis from stem cells, with emphasis on generation of human oocytes, future research objectives for this area of work, and potential clinical applications involving human oogonial stem cells.
Three experts in regenerative medicine explore the evidence and expanding future clinical applicability of the human ovarian and endometrial stem cell population, and tissue engineering of reproductive organs and tissues.
Almost half of the general public supports posthumous reproduction. Age, education, income, political party, currently attempting conception, supporting in vitro fertilization, and organ donation were all associated with support.
Leading medical societies devoted to the care of menopausal women agree that the decision to initiate hormone therapy should be for the indication of treatment of menopauserelated symptoms.
Conventional hormone therapy is preferred over compounded hormone therapy given the available data.
Author:
Barbara Jean Stegmann, M.D., M.P.H.…
By effectively preventing OHSS, the antagonist protocol with GnRH-a trigger is a better option for treating women with PCOS than in vitro maturation (IVM).
This study suggests that in thalassemic men, blood transfusion is associated with significant acute enhancement of sperm parameters and increased concentrations of serum T, LH, FSH, and IGF-1.
PICSI and Sperm Slow allow comparable clinical efficiency in selecting HA-bound spermatozoa.
More knowledge about the development of the androgenic and spermatogenic compartments of the Klinefelter testis is needed to formulate a rational approach to fertility optimization and preservation in these men.
This study suggests that Duarte1 and Duarte2 genotypes do not appear to play a role in the association from galactose intake, possible ovarian dysfunction, and the link with ovarian cancer.
While AFC and age are predictive of live birth following IVF treatment, AFC demonstrates a stronger positive correlation. This study illustrates post-test probabilities of live birth at individual AFC thresholds.
This study investigated the incidence of failed hCG administration as evidenced by negative serum β-hCG after initial trigger injection, and the ability to salvage such cycles through repeat administration of hCG before retrieval.
The impact of early hormone therapy on fertility outcomes in patients with Klinefelter syndrome is not well understood. Semen or testicular tissue cryopreservation should be considered in affected adolescents to maximize future fertility potential.
This collection of articles written by a series of experts should help all those who deal with Klinefelter syndrome patients develop a much broader and scientifically based understanding of this common condition.
Self-reported psychosocial stress, anxiety, and depression were not associated with fecundity. Any adverse effect of stress or psychological disturbance does not appear to be detectable via the questionnaires administered.
Pregnancies arising from the transfer of frozen thawed IVF embryos have better obstetric and perinatal outcomes based on the observational data.
This study evaluated the effect of short-term postoperative sunitinib administration on reproductive function after surgical uterine abrasion in a rabbit model, and found that it ameliorated adhesion-induced reproductive aberrations.
Author:
Claus Yding Andersen, D.M.Sc.…
Author:
Vasiliki A. Moragianni, M.D.…
Author:
Elizabeth A. Stewart, M.D.…
It is recommended that practitioners defer gamete donors who have confirmed or suspected West Nile virus infections.
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